2025年9月8日 星期一

David Baltimore,大衛·巴爾的摩 現代生物學的一位傑出人物,開啟了對逆轉錄病毒和病毒(包括愛滋病毒)的理解兩著名大學的校長。

 

諾貝爾獎得主、分子生物學家大衛巴爾的摩逝世,享年87歲

他年僅37歲時,就做出了一項挑戰現有生物學原則的發現,並由此開啟了對逆轉錄病毒和病毒(包括愛滋病毒)的理解。


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大衛巴爾的摩,一位留著鬍鬚、戴著眼鏡、身穿深色西裝的男子,坐在一個看起來像禮堂的紅色椅子上。

2018年,大衛·巴爾的摩出席在香港舉行的人類基因組編輯會議。他是現代生物學的一位傑出人物。圖片來源:Vincent Yu/美聯社

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

He was only 37 when he made a discovery that challenged the existing tenets of biology and led to an understanding of retroviruses and viruses, including H.I.V.

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David Baltimore, a bearded man in glasses and a dark suit, sits in a red chair in what appears to be an auditorium.
David Baltimore at a conference about human genome editing in Hong Kong in 2018. He was a towering figure of modern biology.Credit...Vincent Yu/Associated Press

在加州理工學院任職期間,巴爾的摩博士從未停止他自1986年起開始的愛滋病研究。他也領導了一個全國愛滋病政策委員會。他還在阿貝爾森白血病病毒中發現了一種致癌基因,這為研發抗癌藥物格列衛打開了大門。

他懇求其他病毒學家研究愛滋病——但他說,他的懇求收效甚微。

「我說,任何從事病毒學研究的人都有責任參與這個問題來,」巴爾的摩博士說。 “它有可能成為我們這個時代最嚴重的公共衛生災難。但大多數病毒學界人士對此置之不理。他們專注於自己的工作,愛滋病問題已經被高度政治化了。”

During his time at Caltech, Dr. Baltimore never ceased his research into AIDS, which he began in 1986. He also headed a national committee on AIDS policy. And he discovered a cancer-causing gene in the Abelson leukemia virus, which opened the door to the creation of the cancer drug Gleevec.

He pleaded with other virologists to study AIDS — but, he said, his pleas were to little avail.

“I said it is the responsibility of anyone working in virology to get involved in this problem,” Dr. Baltimore said. “It threatens to be the worst public health disaster of our time. But most of the virology community did not respond. They were very involved in their own work and AIDS had gotten very politicized.”


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